LAB ONE N°1 Butyric Acid 60 Capsules

The dietary supplement LAB ONE N°1 Butyric Acid 60 Capsules is a capsule product containing sodium butyrate or sodium salt, an organic compound containing a butyric acid residue . Its chemical name is butyric acid.

Butyric acid is formed in the large intestine during the fermentation of sugars by bacteria of the genera Clostridium spp., Eubacterium spp., Fusobacterium spp., etc. The richest sources of butyric acid in the large intestine are resistant starch, oats, and wheat bran. [1]

Butyric acid is an energy source for enterocytes, the normal cells of the intestinal epithelium. Unfortunately, it is supplied in the diet in too small quantities to fulfill this function.

In addition, this acid helps reduce the severity of diarrhea caused by various causes. It also restores the structural and functional integrity of the intestine and influences normal motility of the digestive tract. Butanoic acid increases the absorption of sodium and thus water in the intestine. It also affects the normalization of bacterial flora.

Interestingly, butyric acid also accelerates the regeneration of damaged intestinal epithelial cells and has an anti-inflammatory effect with a reduction of pro-inflammatory cytokines (IL-6, IL-8, TNF-α) and protects against the escape of bacteria from the intestine into the bloodstream.

Butyric acid deficiency in the gastrointestinal tract can lead to mucosal dysfunction in both the small and large intestine. Inadequate butyric acid concentrations in the intestinal lumen lead to energy depletion in colonocytes, thus impairing epithelial regeneration and maintaining epithelial integrity. [2]

In summary, the dietary supplement LAB ONE N°1 Butyric Acid 60 Capsules is a product with a simple composition in a convenient capsule form, providing butyric acid in the form of sodium butyrate, which increases its bioavailability.

1 Kotunia, A., Pietrzak, P., Guilloteau, P., & Zabielski, R. (2010). Butyric acid in the gastrointestinal tract. Prz Gastroenterol , 5 , 117-22.

2 Banasiewicz, T., Borycka-Kiciak, K., Dobrowolska-Zachwieja, A., Friediger, J., Kiciak, A., Krokowicz, P., ... & Zabielski, R. (2010). Clinical aspects of the use of butyric acid in the dietary treatment of intestinal diseases . Review of Gastroenterology 2010; 5: 329 , 334 .