Acetonitrile CH₃CN - for HPLC Gradient Grade Chromatography

Acetonitrile HPLC Gradient Grade is a high-purity organic solvent for professional high-performance liquid chromatography (HPLC) applications. It is particularly recommended for gradient mode analysis and exhibits low UV absorption and very low fluorescence to ensure baseline stability and precise detection of trace compounds.

Identification Data

• Chemical Name: Acetonitrile
• Synonyms: Methyl cyanide, Ethanenitrile
• Molecular Formula: CH₃CN
• Molar Mass: 41.05 g/mol
• CAS Number: 75-05-8
• EC Number (EINECS): 200-835-2

Physicochemical Properties

• Form: liquid
• Color: colorless
• Odor: aromatic
• Melting Point: -46°C
• Boiling Point: 81°C
• Autoignition Temperature: 524°C
• Flash Point: 2°C
• Explosive Limits: 3-16% vol.
• Viscosity (20°C): 0.357 mPa-s
• Vapor Pressure (20°C): 97 mbar
• Density (20°C): 0.78 g/cm³
• Solubility: completely miscible with water, alcohol, ethyl ether, acetone, benzene
• log POW: -0.34
• Vapor Density (air=1): 1.42
• Critical Temperature: 274.7°C
• Critical Pressure: 4.83 MPa
• Refractive Index (20°C): 1.344

Quality Parameters

• Content (GC): min. 99.9%
• Water (KF): max. 0.015%
• Residue on Evaporation: max. 0.0005%
• Acidity: max. 0.0005 meq/g

UV Transmittance (1 cm cell, H₂O)

• 200 nm: min. 80%
• 210 nm: min. 88%
• 220 nm: min. 94%
• 230 nm: min. 98%
• 240 nm: min. 99%

Fluorescence

• 365 nm (vs. quinine): max. 1 ppb

Transport Classification

• RID/ADR: Class 3, Packing Group II
• UN: 1648

Hazard Statements (H)

• H215: Flammable product
• H302: Harmful if swallowed
• H312: Harmful in contact with skin
• H319: Causes serious eye irritation
• H332: Harmful if inhaled

Precautionary Statements (P)

• P210: Keep away from heat/sparks/open flames
• P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
• P403+P235: Store in a well-ventilated place. Keep cool

This product is intended for professional laboratory use only. Not for pharmaceutical, cosmetic, or food purposes.